I've been trying the mod QBar recently.
It's a very simple mod that automatically puts usable quest items on a bar for you. It makes questing easier, as the button for the whatever items you need to use is always in the same place. No need to dig through bags, or try and keep some regular bar space free. No need to worry about cleaning up unused icons after the quest.
It's a great small mod that does one thing, but does it very well.