Some of the comments on the last post have brought up complexity. Yes, the optimum pattern is relatively complex. But there are other patterns which are a lot less complex, and only slightly worse.
For example, with that Chaotic meta-gem, you could follow Suicidal Zebra's pattern of Purple gems + 1 Blue gem. It simplifies the gemming a great deal, and is only a little bit worse. You could even go Purple in Red/Blue slots and Green in Yellow slots (or Yellow and 1 extra Blue in a Blue Socket), and that would easily get you the meta-gem activation and your socket bonuses.
There are other meta-gems you could use. Maybe they aren't as good as this one, but it would make gemming easier if you were concerned about that.
There's a thread espousing the same thing for classes on the DPS forums. The poster is complaining that the optimum rotation is getting too complicated and asks for some specs to have a simpler optimum rotation, but not do as much damage.
I'm not sure I really understand this request. You can alway simplify your rotation and do just a little bit less damage. For example, if you're a Retribution paladin, drop Holy Wrath and Consecration entirely. Your damage will go down slightly, but that rotation would be a lot easier to manage.
Or take Destro warlocks, which is the poster's concern. Drop Corruption and maybe Chaos Bolt. Don't worry about the Imp Soulfire buff. Unfortunately, the Shadow Bolt buff is a group buff so it's harder to drop. But now your rotation is just Immolate, Conflag, Bane, Incinerate, and instant Soulfires when they proc. That's a lot easier to keep track of.
I thought this was the ideal that people wanted. A moderately complex rotation for good damage, or a highly complex rotation for a bit more damage. An easy gemming strategy for good effectiveness, or a complex gemming strategy for optimum effectiveness.
When reforging was introduced, I seemed to be the only person who didn't like it, because I saw it would introduce this level of complex tweaking. But everyone else seemed to think it was the greatest thing since sliced bread. I don't really see the difference between reforging and this gemming strategy. If anything, this meta-gem is easier to deal with than hit caps, expertise caps, and haste soft-caps.
So where then does this vision of complexity go wrong?